I could do with slightly more information yet seing as for some odd reason I'm not that good at home but pretty good away I think I should be able to help you out.
One essential thing is the team talk. Unless you are say man utd against say kidderminster harriers grannies reserves, then you probably shouldn't say in your teamtalk "I expect you to win" when away from home. The squad would feel you are expecting too much of them and would therefore crumble under pressure most probably. Usuaally the better option is "Wish the team luck for the match ahead".
As for formations and what not, I personally use exactly the same tactics both home and away and my performances don't seem to be that different from each other. I use like you a flat 4-4-2 and am slightly defensive both times, possibly due to the fact I'm in a higher league because I didn't try this before, but since I began using it I was on the verge of relegation and ended up surviving comfortably.
The possibility may be that you are getting slightly unlucky and the other teams are just playing well, or it may be that your formation is not a good one to face up to the opposition formation.
Another thing you could do would be instead of adjusting team instructions, adjust instructions for individual players and change to a more defensive formation. One simple thing I tried instead of a 4-4-2 was in a league cup game away from home against championship side millwall I switched to a 4-1-3-1-1 formation, and I won the match 1-0 even though Millwall didn't play that badly (I'm in charge of Lincoln City who I got promoted to League 1).
I personally don't think the width should make any difference but it depends on the squad you have. If you have a big target man upfront and want to counter attack then using two wingers to push up in a counter attack and whip in crosses could get you an extra goal you need. Also the tempo you use wouldn't really matter either - but playing with a slow tempo and trying to counter attack doesn't work extremely well - because you would probably be using short passing and not moving especially fast - therefore causing your opponents to get organised in time before your counter attack can be at all successful.
If you are leaking a lot of goals, you could always try using a sweeper...
Lot of things to take on but I hope they will help you out. However since I don't know what quality of team you are using some people may disagree with what I say as I am inexperienced with using the better teams