Hi Sussex,
I am playing West Ham (pre-patch), and have similar squad

. What I have found working best for me against small sides is:
-442 (I usually play diamond, but flat should be fine too);
- focus passind down both flanks;
- make AVB and Bale (in my case AVB and Marcelo)
forward run often (only against weaker teams!)and cross ball mixed;
- put short farrow on Walcott and Adu;
- push defensive line a little bit up, but make sure your DCs on man marking (to avoid counter attacks).
- place one of your strickers into Target man box but do not use target man. If you choose Owen then supply to feet, if Ashton - mixed. Ask TM hold up ball.
- give Reo Coker free role. He is very good running from 16 to 16 and if he has normal mentality he will support both attack and defense.
- global mentality normal. The reason is if you go attacking, it is exactly what AI expects. I have individual settings for some players (sort Rule of One settings).
One more thing. If your current setting are very different from my suggestions, it may take some time to adjust. So maybe you need to change settings gradually. Also a good strong TM may help (Bianchi (sp), Klose, Okaka etc.) if you can afford one.
Hope it helps