Goalkeeper- As Given is getting older, you'll want to invest for the future. Perhaps Vincent Enyeama or Marcelo Grohe?
Left-back- Both good options. If you have enough money (and he wants to come) maybe look at Marcelo from R Madrid (5.5 mil release clause)
Defensive Midfield- Dessena would be fine as back up. Banega is another obvious choice. For more experience, Torrado from Cruz Azul has never disppointed for ME.
Central Defense- Wouldn't count on Edgar. Definitely Breno (Sao Paulo) for the future but for the here and now perhaps Carlos Salcido or Diego Lugano. Also, just seen Vidal from Leverkusen, great stats although he probably won't leave.
Attacking midfield- Luka Modric, Marko Marin and Ivan Rakitic have always been good for me. For something different, try Anton Sosnin from Zenit St Peterburg.
Striker- Genero Zeefuik and Henri Saivet anre definitely ino Owen's class (or better) but need a little nuturing to bring out their immense talent. Amauri from Palermo is available for around 9 mil at the start of the game but Lyon seem to always bid for him so try him if you have suffcient funds.
Hope this helps!