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Liverpool's Mohamed Sissoko and John Arne Riise will miss Tuesday's Champions League match against Porto.
Left-back Riise is ruled out of the Group A encounter with a groin injury he picked up on international duty with Norway last week.
Midfielder Sissoko and left winger Harry Kewell will also fail to make the trip to Portugal.
But the left-sided Fabio Aurelio is back in the squad after a lengthy absence with an Achilles tendon injury.
"Fabio is back which is good news for us," said Reds manager Rafael Benitez.
"He has worked hard to recover from his injury and could be a useful asset for us."
Liverpool finished as runners-up last season after losing to AC Milan in the final and Benitez will face a dilemma in terms of his starting line-up in attack.
Peter Crouch and Andriy Voronin got the nod for the 0-0 draw with Portsmouth on Saturday but Fernando Torres is expected to start with Dirk Kuyt also in contention.
Champions League (CL) - only group phase matches and beyond of this competition which began in 1992-93.
Champions Cup/Champions League - all matches played since it began in 1955-56 including qualification matches.
European matches - all matches played in the major European tournaments (Fairs Cup, Uefa Cup, Cup Winners' Cup, Champions Cup, Champions League).
Uefa Super Cups, Intertoto Cups and the old Intercontinental Cup competition are excluded.
Head-to-heads
Group A is the only group that contains more than one former winner of the Champions League.
FC Porto and Liverpool have met twice, both matches taking place in the quarter-finals of the 2000-01 Uefa Cup. The first leg finished in a goalless draw at the Das Antas. Liverpool claimed the tie courtesy of a 2-0 victory at Anfield; Danny Murphy and Michael Owen were both on target within five minutes of each other in a 2-0 triumph.
European history
FC Porto won the Champions Cup in 1987 and the Champions League in 2004. They have won 38, drawn 27 and lost 35 of 100 Champions League matches.
Liverpool, last year's beaten finalists, are making their sixth group stage appearance having made their debut in the competition in 2001.
Current European form
FC Porto have not lost any of their last six European home matches.
The last opponents to triumph at the Estadio do Dragao were FC Artmedia Bratislava on 28 September 2005 (2-3).
Player and disciplinary info
The most experienced player in the current Porto squad as far as this competition is concerned is defender Pedro Emanuel, who has made 34 CL appearances. Lucho Gonzalez and Lisandro Lopez are the Oporto clubs' leading scorers in the current squad with four career CL goals each.
Jamie Carragher is Liverpool's all-time record holder with 53 CL appearances for the Merseysiders. Steven Gerrard and Peter Crouch lead the current squad members in CL goalscoring, with six goals a piece.
Other miscellaneous facts
FC Porto lead the Portuguese league after four straight victories.
Liverpool are yet to lose a Premier League match this season.
Big Match Stats source: Infostrada Sports
Think we'll line up like this:
Reina
Finnan
Carragher
Agger
Arbeloa
Benayoun
Alonso
Masherano
Babel
Kuyt
Torres
Hopefully Torres starts his first ever game in Europe. Think we'll rest Gerrard too.
Prediction: 1-0 to us. or it'll be a 0-0 bore of course.
Gerrard and Torres definite starters imho. Not sure we can afford to take this one for granted. Plus we've got Birmingham on saturday so we might be able to rest a couple of players then. I'd take a point.
Porto vs Liverpool, CL, KO. 7:45 Tuesday 
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