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Limited support/transferability from what I remember. I've got a Vista OEM (since it came out) and i've had absolutely no problem with it so it gets a :thup:.
You can transfer it, but not as many times.
You don't get support which is true. But really, who here has ever phoned up MS when their computer crashes?
As has already been said, I had an OEM version of XP and I've never had any trouble with it at all. Everything the same except that you probably won't get a manual/user guide with it and of course the limited transferability.
As it happens there are many systems that are very similar specs to this (from 99%+ positive feedback sellers) on eBay at the moment for about half of the cost you are looking at with similar warranties if you are shopping around and don't mind buying it from somewhere other than a well known retailer.
Think I will go for the OEM version then, but cant see anywhere on Ebay that has a similar spec, with 22" monitor that is a significant amount cheaper. If you could post a link I would take a look