Defensively, you work out what they're good at, you work out how to stop them doing that, and finally work out who you've got that can do that.
Offensively, you do what your players seem to do best/least badly, unless they seem to be doing something that'll stop you doing that.
Sorry if that's not much help, but all I wanted to do was help you ask yourself the right questions. LLM is about improving your tactical abilities with trial, error and common sense. Well... that's the idea. More often than not it ends in failure, but hey, it's fun