I have found 1 striker to be more successful, with lots of support from midfield, but I am looking to make 2 strikers work better.. I guess you can make it work with either way as long as you adjust your tactics as you go along
If your the underdog and want to play on the counter then I think 2 strikers is better.
If your the favourites and playing patient buildup then 1 striker is better. The extra man in midfield gives more options for a passing game and midfield runners are harder to mark than strikers.
I tend to switch between a 442 and a 4411 setup.
It all depends on how offensive I am.
If my team plays fast passing based I use two strikers. If I play slower, build up based I use one AMC and one striker. They both work pretty well with those combinations.